Sulfonylurea Drugs Increase The Risk Of Heart Disease

Sulfonylurea Drugs Increase The Risk Of Heart Disease.

New investigation shows that older hoi polloi with type 2 diabetes who take drugs known as sulfonylureas to condescend their blood sugar levels may face a higher risk for heart problems than their counterparts who ingest metformin. Of the more than 8500 people aged 65 or older with paradigm 2 diabetes who were enrolled in the trial, 12,4 percent of those given a sulfonylurea drug experienced a nub attack or other cardiovascular event, compared with 10,4 percent of those who were started on metformin acnespotgel. In addition, these hub problems occurred earlier in the course of treatment among those people taking the sulfonylurea drugs, the weigh showed.

The head-to-head comparison trial is slated to be presented Saturday at the American Diabetes Association annual convocation in San Diego. Because the findings are being reported at a medical meeting, they should be considered introductory until published in a peer-reviewed journal With type 2 diabetes, the body either does not compose enough of the hormone insulin or doesn't use the insulin it does produce properly.

In either case, the insulin can't do its job, which is to utter glucose (blood sugar) to the body's cells. As a result, glucose builds up in the blood and can bring havoc on the body. Metformin and sulfonylurea drugs - the latter a stratum of diabetes drugs including glyburide, glipizide, chlorpropamide, tolbutamide and tolazamide - are often all the first medications prescribed to lower blood sugar levels in people with type 2 diabetes.

The findings are important, the researchers noted, partly because sulfonylurea drugs are commonly prescribed in the midst the hoary to lower blood glucose levels. In addition, cardiovascular illness is the leading cause of death among people with type 2 diabetes. For several reasons, however, the changed study on these medications is far from the final word on the issue.

For one, people who are started on the sulfonylureas as an alternative of metformin are often sicker to begin with, said Dr Spyros G Mezitis, an endocrinologist at Lenox Hill Hospital in New York City. Metformin cannot be prescribed to individuals with decided kidney and heart problems. Both medications lower blood glucose levels, but go about it in unreservedly different ways.

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People Often Die In Their Sleep

People Often Die In Their Sleep.

People with drowse apnea and hard-to-control enormous blood pressure may see their blood pressure drop if they treat the be in the arms of Morpheus disorder, Spanish researchers report. Continuous positive airway pressure (CPAP) is the pillar treatment for sleep apnea, a condition characterized by disrupted breathing during sleep. The nod off disorder has been linked to high blood pressure cheapest. Patients in this study were taking three or more drugs to soften their blood pressure, in addition to having sleep apnea.

Participants who used the CPAP device for 12 weeks reduced their diastolic blood persuasion (the bottom number in a blood pressure reading) and improved their overall nighttime blood pressure, the researchers found. "The primacy of sleep apnea in patients with against high blood pressure is very high," said lead researcher Dr Miguel-Angel Martinez-Garcia, from the Polytechnic University Hospital in Valencia "This rest apnea healing increases the probability of recovering the normal nocturnal blood pressure pattern.

Patients with resistant maximum blood pressure should undergo a sleep study to rule out obstructive sleep apnea, Martinez-Garcia said. "If the long-suffering has sleep apnea, he should be treated with CPAP and undergo blood arm monitoring". The report, published in the Dec 11, 2013 issue of the Journal of the American Medical Association, was partly funded by Philips-Respironics, maker of the CPAP technique used in the study.

The CPAP pattern consists of a motor that pushes air through a tube connected to a mask that fits over the patient's pronounce and nose. The device keeps the airway from closing, and thus allows non-stop sleep. Sleep apnea is a common disorder. The pauses in breathing that patients sense can last from a few seconds to minutes and they can occur 30 times or more an hour.

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Tweets of 10th June


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Ophthalmologists Told About The New Features Of The Human Eye

Ophthalmologists Told About The New Features Of The Human Eye.

Simply imagining scenes such as a unclouded era or a night sky can cause your pupils to shift size, a new study finds. Pupils automatically dilate (get bigger) or decrease (get smaller) in response to the amount of light entering the eye problem solutions. This study shows that visualizing night-time or bright scenes affects people's pupils as if they were actually seeing the images.

In one experiment, participants looked at a shelter with triangles of different levels of brightness. When later asked to create those triangles, the participants' pupils varied in size according to each triangle's brightness hypercet. When they imagined brighter triangles, their pupils were smaller, and when they imagined darker triangles, their pupils were larger.

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Teens Need Regularly Make Medical Examination

Teens Need Regularly Make Medical Examination.

Doctors often ignore to have a confabulation with their teen patients about sexuality issues during their annual physical, a new study reveals. This results in missed opportunities to notify and counsel young people about ways to help frustrate sexually transmitted diseases and unwanted teen pregnancies, the researchers suggested weight. The study, published Dec 30, 2013 in JAMA Pediatrics, interested 253 teens and 49 doctors from 11 clinics from the Raleigh/Durham, North Carolina area.

One-third of these teens did not require questions about coition or discuss their sexual activity, sexuality, dating or sexual identity during their yearly check-ups, the muse about found. The researchers, led by Stewart Alexander of the Duke University Medical Center, recorded conversations between the teens and their doctor, and analyzed how much take was spent talking about sex amond oil k kya fyede h hair m lgane s. They also considered the involvement of teens in these discussions.

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