The Flu Vaccine Is Little Effect On Men

The Flu Vaccine Is Little Effect On Men.

The flu vaccine is less capable for men than women, and researchers at Stanford University maintain they've figured out why. The manful hormone testosterone causes genes in the immune methodology to produce fewer antibodies, or defense mechanisms, in response to the vaccine, they found visit website. "Men, typically, do worse than women in protected response to infection and vaccination," said Stanford research associate David Furman, the lead study investigator.

For instance, men are more susceptible to bacterial, viral, fungal and parasitic infection than women. And men's safe systems don't come back as robustly as women's to vaccinations against flu, yellow fever, measles, hepatitis and many other diseases get more info. For the study, published online Dec 23, 2013 in the Proceedings of the National Academy of Sciences, the researchers analyzed the blood of nearly 90 adults after they received a seasonal flu shot.

Men with the highest testosterone levels had the worst comeback to the flu vaccine across the board. Testosterone is tied to enduring masculine fleshly characteristics, such as muscle strength, beard growth and risk-taking. "We found a set of genes in men that when activated caused a unlucky response to the vaccine, but were not involved in female response. Some of these genes are regulated by testosterone".

It's testosterone's impression on these genes that causes the poor vaccine response. "This has a lot of implications for vaccine development". Vaccine rejoinder might be better if men were given twice the dose, he suggested, or it is possible that if testosterone levels were reduced. The whole picture isn't at bottom clear or simple. Men's weaker response to the flu vaccine is only seen for some strains of flu.

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In The USA Hypertensive Diseases Have Become Frequent

In The USA Hypertensive Diseases Have Become Frequent.

The division of Americans reporting they have loaded blood pressure rose nearly 10 percent from 2005 to 2009, federal fitness officials said 2013. High blood pressure - or hypertension, a main risk factor for heart disease and stroke - affects nearly one-third of Americans, said Fleetwood Loustalot, a researcher at the National Center for Chronic Disease Prevention and Health Promotion, function of the US Centers for Disease Control and Prevention learn more here. About 26 percent of Americans said they had capital blood to in 2005, and more than 28 percent reported squiffy blood pressure in 2009 - a nearly 10 percent increase.

And "Many factors provide to hypertension," Loustalot said, including obesity, eating too much salt, not exercising regularly, drinking too much spirits and smoking. "What we are really concerned about as well is that people who have high blood apply pressure are getting treated. Only about half of those with hypertension have it controlled site here. Uncontrolled hypertension can lead to negative haleness consequences like heart attacks and strokes".

Of the study participants who said they had high blood coercion in 2009, about 62 percent were using medication to control it. Loustalot said the widen in the prevalence of high blood pressure is largely due to more awareness of the problem.

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The Earlier Courses Of Multiple Sclerosis

The Earlier Courses Of Multiple Sclerosis.

A treatment that uses patients' own simple blood cells may be able to reverse some of the effects of multiple sclerosis, a groundwork study suggests. The findings, published Tuesday in the Journal of the American Medical Association, had experts cautiously optimistic. But they also stressed that the library was small - with around 150 patients - and the benefits were meagre to people who were in the earlier courses of multiple sclerosis (MS) get more information. "This is certainly a auspicious development," said Bruce Bebo, the executive vice president of delving for the National Multiple Sclerosis Society.

There are numerous so-called "disease-modifying" drugs available to expound MS - a disease in which the immune system mistakenly attacks the protective sheath (called myelin) around fibers in the intellect and spine, according to the society. Depending on where the damage is, symptoms number muscle weakness, numbness, vision problems and difficulty with balance and coordination i found it. But while those drugs can unpunctually the progression of MS, they can't reverse disability, said Dr Richard Burt, the model researcher on the new study and chief of immunotherapy and autoimmune diseases at Northwestern University's Feinberg School of Medicine in Chicago.

His set tested a new approach: essentially, "rebooting" the vaccinated system with patients' own blood-forming stem cells - primitive cells that fully fledged into immune-system fighters. The researchers removed and stored stem cells from MS patients' blood, then reach-me-down relatively low-dose chemotherapy drugs to - as Burt described it - "turn down" the patients' immune-system activity. From there, the bows cells were infused back into patients' blood.

Just over 80 commonalty were followed for two years after they had the procedure, according to the study. Half epigram their score on a standard MS disability scale fall by one point or more, according to Burt's team. Of 36 patients who were followed for four years, nearly two-thirds aphorism that much of an improvement. Bebo said a one-point trade on that scale - called the Expanded Disability Status Scale - is meaningful. "It would unequivocally improve patients' quality of life".

What's more, of the patients followed for four years, 80 percent remained emancipate of a symptom flare-up. There are caveats, though. One is that the cure was only effective for patients with relapsing-remitting MS - where symptoms outburst up, then improve or disappear for a period of time. It was not helpful for the 27 patients with secondary-progressive MS, or those who'd had any appear of MS for more than 10 years.

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Athletes Often Suffer A Concussion

Athletes Often Suffer A Concussion.

Altitude may agitate an athlete's imperil of concussion, according to a new study believed to be the first to examine this association. High school athletes who vie with at higher altitudes suffer fewer concussions than those closer to sea level, researchers found in Dec, 2013. One tenable reason is that being at a higher altitude causes changes that commission the brain fit more tightly in the skull, so it can't move around as much when a player suffers a head blow read more. The investigators analyzed concussion statistics from athletes playing a row of sports at 497 US exorbitant schools with altitudes ranging from 7 feet to more than 6900 feet above briny level.

The average altitude was 600 feet. They also examined football separately, since it has the highest concussion percentage of US high school sports At altitudes of 600 feet and above, concussion rates in all momentous school sports were 31 percent lower, and were 30 percent mark down for football players, according to the findings recently published in the Orthopaedic Journal of Sports Medicine.

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Passive Smoking Of Children Is Possible Through General Ventilation

Passive Smoking Of Children Is Possible Through General Ventilation.

Children who conclude in smoke-free apartments but have neighbors who inconsiderable up suffer from exposure to smoke that seeps through walls or shared ventilation systems, young research shows. Compared to kids who lodge in detached homes, apartment-dwelling children have 45 percent more cotinine, a marker of tobacco exposure, in their blood, according to a review published in the January issue of Pediatrics resource. Although this study didn't countenance at whether the health of the children was compromised, previous studies have shown physiologic changes, including cognitive disruption, with increased levels of cotinine, even at the lowest levels of exposure, said scan author Dr Karen Wilson.

And "We mark that this research supports the efforts of people who have already been moving shortly before banning smoking in multi-unit housing in their own communities," added Wilson, an assistant professor of pediatrics at Golisano Children's Hospital at the University of Rochester Medical Center in New York. Vince Willmore, failing president of communications at the Campaign for Tobacco-Free Kids, agreed. "This learning demonstrates the matter of implementing smoke-free policies in multi-unit housing and of parents adopting smoke-free policies in all homes" homepage here. Since smoke doesn't discontinue in one place, Willmore said only complete smoke-free policies provide effective protection.

The authors analyzed data from a chauvinistic survey of 5002 children between 6 and 18 years old who lived in nonsmoking homes. The children lived in unattached houses, attached homes and apartments, which allowed the researchers to dream of if cotinine levels varied by types of housing. About three-quarters of children living in any friendly of housing had been exposed to secondhand smoke, but apartment dwellers had 45 percent more cotinine in their blood than residents of disentangled houses. For white apartment residents, the difference was even more startling: a 212 percent rise vs 46 percent in blacks and no increase in other races or ethnicities.

But a pre-eminent limitation of the study is that the authors couldn't separate other potential sources of exposure, such as kinfolk members who only smoked outside but might carry particles indoors on their clothes. Nor did it take into chronicle day-care centers or other forms of child care that might contribute to smoke exposure.

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The Device That Avoids Open Heart Surgery With Artificial Valve Does Not Work

The Device That Avoids Open Heart Surgery With Artificial Valve Does Not Work.

If an also phony consideration valve derived from a cow or pig fails to be employed properly, researchers say implanting a mechanical valve up the river the artificial valve could be an option for high-risk patients "Once expanded and opened, the new valve opens and functions similarly to the patient's own valve.

The interest is that failing surgical valves can be replaced without the penury for open-heart surgery," study lead author Dr John G Webb, medical superintendent of Interventional Cardiology and Interventional Research at St Paul's Hospital in Vancouver, Canada, explained in an Ameruican Heart Association report release click for source. Webb and colleagues account on 24 high-risk patients who underwent surgery that transplanted a new artificial valve into the existing imitation one.

The valves were inserted through a catheter - either via a tiny slash between the ribs, or through a leg blood vessel - and expanded with the help of balloons that pushed the loved valves away. The strategy isn't appropriate in all cases. Still, "patients may retake more rapidly, and the concerns about major surgery are reduced". The researchers report that the traditional healing - a new open-heart operation - is very risky. The study was reported April 12 in the newspaper Circulation.

Heart Valve Diseases, also called: Valvular heart disease. Your understanding has four valves. Normally, these valves open to let blood flow through or out of your heart, and then seal to keep it from flowing backward. But sometimes they don't work properly.

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tag : valve heart valves surgery mitral called blood problems properly

Scientists Have Submitted A New Drug To Treat HIV

Scientists Have Submitted A New Drug To Treat HIV.

Scientists are reporting ahead but auspicious results from a new drug that blocks HIV as it attempts to invade forgiving cells. The approach differs from most current antiretroviral therapy, which tries to channel the virus only after it has gained entry to cells helpful hints. The medication, called VIR-576 for now, is still in the advanced phases of development.

But researchers say that if it is successful, it might also circumvent the drug resistance that can sap standard therapy, according to a report published Dec 22 2010 in Science Translational Medicine. The unexplored approach is an attractive one for a number of reasons, said Dr Michael Horberg, president of HIV/AIDS for Kaiser Permanente in Santa Clara, California continue. "Theoretically it should have fewer attitude effects and indeed had minimal adverse events in this study and there's probably less of a chance of departure in developing resistance to medication," said Horberg, who was not involved in the study.

Viruses replicate inside cells and scientists have eat one's heart out known that this is when they tend to mutate - potentially developing new ways to hold at bay drugs. "It's generally accepted that it's harder for a virus to mutate surface cell walls".

The new drug focuses on HIV at this pre-invasion stage. "VIR-576 targets a part company of the virus that is different from that targeted by all other HIV-1 inhibitors," explained study co-author Frank Kirchhoff, a professor at the Institute of Molecular Virology, University Hospital of Ulm in Ulm, Germany, who, along with several other researchers, holds a tangible on the revitalized medication. The target is the gp41 fusion peptide of HIV, the "sticky" end of the virus's outer membrane, which "shoots have a weakness for a 'harpoon'" into the body's cells, the authors said.

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Mandatory Health Insurance In The United States

Mandatory Health Insurance In The United States.

The well-being security industry announced Wednesday that the payment deadline for those who buy health insurance through brilliance and federal exchanges under the final provision of the Affordable Care Act, also known as Obamacare, has been extended to Jan 10, 2014. The deadline was extended to arrive at sure no one experiences any inconsistency in coverage this January, according to a statement on the website of America's Health Insurance Plans (AHIP), a occupation group that represents the lion's share of the industry view website. Earlier this month, Obama administration officials had said that fettle insurers must accept payment up until Dec 31, 2013 for coverage that begins the following day, and recommended that the pay deadline be extended further.

The deadline for selecting a health insurance intend remains Dec 23, 2013. Roughly 365000 people had selected a health representation by the end of November, a number well below initial projections. Those low numbers have been linked to the fumbled runabout in October of HealthCare dot gov, the federally run health insurance exchange check this out. Many consumers in the 36 states served by the federal swop encountered long lag times, timed-out net pages and other bugs while attempting to apply for coverage and enroll in a plan.

Most of these problems have since been ironed out, vigorousness officials have said. Now that HealthCare dot gov is said to be working well for most users, efforts are focused on ways to stand behind that the uninsured and those whose health plans are being cancelled don't drop off through the cracks. "The short time period in which consumers must complete these steps and have their enrollment processed, combined with the persistent technical difficulties associated with HealthCare dot gov, could intermediate that for some consumers, coverage may not be able to begin Jan 1, 2014," the AHIP said in its statement.

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Worries About Job Losses Increase The Chances Of Heart Attack And Stroke

Worries About Job Losses Increase The Chances Of Heart Attack And Stroke.

Women who have taxing jobs with dwarf conduct over their busy days are at higher imperil for heart attacks or the need for coronary bypass surgery, new digging suggests. Furthermore, worrying about losing one's job also raised the odds of having cardiovascular plague risk factors such as high blood pressure and higher cholesterol levels - but not factual heart attacks, stroke or death, the researchers said example. The study, presented Sunday at the annual rendezvous of the American Heart Association in Chicago, breaks new initiate for being one of the first to look at the effect of work-related stress on women's health.

Most previous studies have focused on men and, yes, those studies found that occupation stress upped males' odds for cardiovascular disease, too. Women comprise inhumanly half of the US workforce today, with 70 percent of all women holding some thoughtful of job, said study senior author Dr Michelle A Albert, an fellow physician at Brigham and Women's Hospital in Boston source. Albert and her colleagues looked at more than 17000 female vigorousness professionals, with an average age of 57, who showed no signs of cardiovascular ailment at the beginning of the study.

Participants responded to statements about how draining their job was, such as - "My work allows me to make a lot of decisions on my own" or "My job requires that I master new things" or "My job requires working very fast. Job strain involving subconscious demand and decision latitude are tied into the concept of skill, how you are allowed to be at your job, is your hassle repetitive, does it require you to work at a fast pace".

Over 10 years of follow-up, the researchers well-known that women with high job strain - demanding jobs over which they had little control - were more acceptable to be sedentary and to have high cholesterol. They were also at almost double the risk for a heart attack and at a 43 percent higher jeopardy to undergo a bypass procedure. The researchers found no significant link between robbery strain and either stroke or risk for death.

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tag : women heart stroke health researchers cardiovascular percent study higher

Prevention Of Atherosclerosis By Diet Of Fruits And Vegetables

Prevention Of Atherosclerosis By Diet Of Fruits And Vegetables.

Children who take a aliment rich in fruits and vegetables may be able to help ward off atherosclerosis in adulthood, a predecessor of heart disease, a new study suggests. And a second new analysis found that children as young as 9 years old may already be exhibiting health problems such as high blood influence that put them at risk of heart disease as adults more. Both reports, from researchers in Finland, are published in the Nov 29, 2010 online issue of Circulation.

Commenting on the first study, Dr David L Katz, commander of the Yale University School of Medicine's Prevention Research Center, who was not complex with the study, noted that it had taken knowledge about diet and heart health a step further. Atherosclerosis is a shape in which plaque - a sticky substance consisting of fat, cholesterol, and other substances found in the blood - builds up middle the arteries, eventually narrowing and stiffening the arteries and matchless to heart problems go here. It's a process that can take years, even decades, and this study shows that nourishment even in childhood - helps prevent the condition.

And "We certainly, before this study, knew that vegetable and fruit intake were capable for our health in general, and good for cardiovascular health in particular". For the head study, researchers led by Dr Mika Kahonen, chief physician in the Department of Clinical Physiology at Tampere University Hospital in Finland, looked at lifestyle factors and quantified the hammering of 1622 people who took part in the Cardiovascular Risk in Young Finns Study. The participants ranged in era from 3 to 18 when the study began and were followed for 27 years.

The researchers also assessed "pulse billow velocity" - a measure of arterial stiffness. The researchers found that those junior people who ate fewer vegetables and fruits had higher pulse fluctuate velocity, which means stiffer arteries. But those who ate the most vegetables and fruits had a pulse wave 6 percent drop than people who ate fewer fruits and veggies. Because arterial stiffness is linked with atherosclerosis, adamantine arteries makes the heart work harder to pump blood.

Besides glum fruit and vegetable consumption, other lifestyle factors such as lack of physical activity and smoking in adolescence was associated with pulse wave strength in adulthood, the researchers said. "These findings suggest that a lifetime gauge of low consumption of fruits and vegetables is related to arterial stiffness in pubescent adulthood," Kahonen said in a news release from the American Heart Association, which publishes Circulation. "Parents and pediatricians have yet another point to encourage children to consume high amounts of fruits and vegetables".

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tag : heart study children disease factors researchers fruits blood arteries



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