Treatment Of Heart Attack With The Help Of Stem Cells From Belly Fat

Treatment Of Heart Attack With The Help Of Stem Cells From Belly Fat.

Stem cells bewitched from the belly affluent of 10 sincerity attack patients managed to improve several measures of heart function, Dutch researchers report. This is the before all time this type of therapy has been used in humans, said the scientists, who presented their findings Tuesday at the American Heart Association's annual meet in Chicago beautiful older women erotika. But the improvements, though less dramatic in this small group of patients, were not statistically significant, probably due to the reduced number of participants in the study.

And another expert urged caution when interpreting the results. "The indicator issue is whether a treatment makes us live longer or feel better," said Dr Jeffrey S Borer, seat of the department of medicine and of cardiovascular medicine at the State University of New York (SUNY) Downstate Medical Center in New York City full report. This work only looked at "surrogates," message measures of heart function that might predict better future health in the patient.

So "This cannot be interpreted as if they speedily represent positive clinical outcomes. These certainly are favourable stem cell data, but there's a great deal more to do before it is possible to know whether this is a viable therapy".

Another caveat: All the patients in this whirl were white Europeans. The study authors believe the results could be extrapolated to much of the US population, but not certainly to people who aren't white. Fat tissue yields many more staunch cells than bone marrow (which has been studied before) and is much easier to access.

In bone marrow, 40 cubic centimeters (cc) typically gain about 25000 stem cells, which is "not nearly enough to treat individuals with," said study author Dr Eric Duckers, head of the Molecular Cardiology Laboratory at Thoraxcenter, Erasmus University Medical Center in Rotterdam. To get enough cells to toil with, those prow cells would have to be cultured, a process that can take six to eight weeks.

By contrast, 100 cc's of prosperity tissue yield millions of stem cells, plenty to chef-d'oeuvre with. A hundred cc's is about the size of a coffee cup - a European coffee cup, not the mega-size of American coffee containers, Duckers emphasized. "With that many cells, you can sequester them and give them to the unyielding right away as they come into the hospital".

All patients in this double-blind, placebo-controlled study (11 men and three women) arrived at the sickbay having suffered a severe heart attack. All then underwent cardiac catheterization to assess blood flow, followed by percutaneous coronary intervention (PCI), more commonly known as angioplasty, to reimburse blood flow.

Within 24 hours of the crux attack, doctors performed liposuction to off fat tissue, isolated 20 million stem cells and gave them back to the patients through a catheter. The infusion took no more than 10 minutes. Ten patients received stop cells and four received a placebo infusion. "It was done very, very quickly, all in the same day".

Six months after the procedure, check cubicle patients had better blood flow (more than triple the class compared to patients getting a placebo), a 5,7 percent increase in heart pumping ability, and a 50 percent reduction in scarring of fundamentals muscle (from 31,6 percent right after the basics attack to 15,4 percent). Placebo patients saw no decrease in scarring.

And "In theory the use of stem-post cells to improve myocardial perfusion blood flow and cardiac performance is very heartening - but to the present time, although many approaches to stem cell use have been tested, there really has not yet been evidence of a clinically fruitful important result. That doesn't mean that stem cell research isn't an superior lead to follow" The Dutch research team is now embarking on a trial that will in the long run enroll 375 heart attack patients at 35 medical centers in the European Union to further evaluate stem cell infusions.

tag : cells patients heart attack placebo percent study blood medical

Post a comment

Private comment



Welcome to FC2!

Latest journals
Latest comments
Latest trackbacks
Monthly archive
Search form
Display RSS link.
Friend request form

Want to be friends with this user.