The Researchers Found That High Blood Sugar Impairs Brain Communication With The Nervous System

The Researchers Found That High Blood Sugar Impairs Brain Communication With The Nervous System.

A embryonic bond between diabetes and a heightened jeopardize of heart disease and sudden cardiac death has been spotted by researchers studying mice. In the different study, published in the June 24, 2010 issue of the journal Neuron, the investigators found that exorbitant blood sugar prevents critical communication between the brain and the autonomic in a dither system, which controls involuntary activities in the body. "Diseases, such as diabetes, that disturb the function of the autonomic perturbed system cause a wide range of abnormalities that include poor control of blood pressure, cardiac arrhythmias and digestive problems," elder author Dr Ellis Cooper, of McGill University in Montreal, explained in a dispatch release from the journal's publisher example. "In most people with diabetes, the malfunction of the autonomic on edge system adversely affects their quality of life and shortens fixation expectancy".

For the study, Cooper and his colleagues used mice with a form of diabetes to examine electrical noteworthy transmission from the brain to autonomic neurons continue reading. This communication occurs at synapses, which are secondary gaps between neurons where electrical signals are relayed cell-to-cell via chemical neurotransmitters.

So "In nourishing individuals, synaptic transmission in the autonomic nervous system is strong and stable; however, if synapses on these neurons malfunction due to some infection process, the link between the nervous system and the periphery becomes disrupted," Cooper said in the communication release. The researchers found that, in mice, stoned blood sugar elevates reactive molecules that contain the oxygen atom (called reactive oxygen species) in autonomic neurons.

This chemical substitution inactivates the neurotransmitter receptors at these synapses. "Our a post provides a new explanation for diabetic-induced disruptions of the autonomic nervous system. This synaptic the blues is apparent as early as one week after the onset of diabetes and becomes more ascetic over time" website. It's important to note that animal studies, while an important part of the scientific process, often wanting to yield similar results in humans.

tag : autonomic system diabetes nervous communication blood neurons researchers synapses

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