New Study On Prevention Of Transfer Of HIV

New Study On Prevention Of Transfer Of HIV.

An antiviral antidepressant may facilitate protect injection drug users from HIV infection, a fresh study finds. The study of more than 2400 injection drug users recruited at 17 medication treatment clinics in Thailand found that daily tablets of tenofovir reduced the risk of HIV infection by nearly 49 percent, compared to lazy placebo pills provillusforwomen. One expert said an intervention to mitigate shield injection drug users from HIV - the virus that causes AIDS - is much needed.

And "This is an portentous study that opens up an additional option for preventing HIV in a hard-to-reach population," said Dr Joseph McGowan, medical cicerone at the Center for AIDS Research and Treatment at North Shore University Hospital in Manhasset, NY. He famed that "HIV infections persist to occur at high rates, with over 2,5 million worldwide and 50000 uncharted infections in the US each year feline. This is despite widespread knowledge about HIV infection and the procedure it is spread, through unprotected sex and sharing needles for injecting drugs".

The participants included in the inexperienced study were followed for an average of four years. During that time, 17 of the more than 1200 patients taking tenofovir became infected with HIV, compared with 33 of an commensurate number of patients taking a placebo, according to the lucubrate published online June 12, 2013 in The Lancet. Further analyses of the results showed that the sheltering effect of tenofovir was highest among those who most closely followed the drug's prescribed regimen.

In this group, the jeopardize of HIV infection was reduced by more than 70 percent, said study leaders Dr Kachit Choopanya and Dr Michael Martin, captain of clinical research for the Thailand Ministry of Public Health-US Centers for Disease Control and Prevention Collaboration. Prior scrutinize has shown that safeguard use of antiviral drugs cuts the risk of sexual transmission of HIV in both heterosexual couples and men who have coitus with men, and also reduces mother-to-child transmission of HIV.

But this is the first study to show that this nearly equal might also be effective among injection drug users. Worldwide, injection drug use is believed to cause one in 10 redone HIV infections. But rates of infection associated with injection drug use are far higher in some areas of the world, such as eastern Europe and median Asia.

In these regions, up to 80 percent of restored HIV infections are caused by injection drug use. According to McGowan, tenofovir is no "silver bullet" that would, on its own, rule out the risk of HIV infection for drug abusers. But it could be a explanation ingredient in reducing the odds.

So "Adoption of this strategy, not as a stand-alone, but in conjunction with needle exchange, counseling, opiate substitution, venereal support and mental health therapy may enable us to get on of this expanding epidemic," McGowan said. He added that the participants in the study were also provided with what's known as "directly observed therapy," where the treat is administered under the observance of a health care worker.

Services as if this, along with monthly HIV testing and condom distribution, might not occur in "real life" care situations, McGowan said, so outcomes might not be as good as in this clinical trial. Another professional agreed that adherence to tenofovir therapy is key to success sexual. Tenofovir "accumulates slowly in the body , making the cover for adherence - which is strongly associated with the efficacy of the drug," said Victoria Richards, subsidiary professor of medical sciences at the Frank H Netter MD School of Medicine at Quinnipiac University, in Hamden, Conn.

tag : study injection tenofovir infection infections users mcgowan health therapy

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